PX Business Designer

📍 Job Overview

Job Title: PX Business Designer

Company: Roche (Genentech)

Location: South San Francisco, California, United States

Job Type: Full-time

Category: Revenue Operations / Business Strategy / Patient Experience Operations

Date Posted: August 5, 2026

Experience Level: Mid-Senior Level (4-7 years professional experience)

Remote Status: Hybrid (3 days/week on-site)

🚀 Role Summary

• This role is central to evaluating the financial viability and scalability of patient experience (PX) initiatives within Roche's Genentech division, requiring a strong blend of financial acumen and strategic thinking.

• The PX Business Designer will translate complex patient experience concepts into robust commercial and financial models, assessing costs, revenue potential, and key performance indicators (KPIs).

• A primary focus will be on quantifying both financial and non-financial value drivers to inform strategic decisions on opportunity prioritization and design trade-offs.

• The role involves developing phased investment models, managing risk assessment through discovery-driven planning, and shaping the business architecture for patient programs, including vendor selection and funding strategies.

• This position demands close cross-functional collaboration with finance, data analytics, commercial teams, and experience design to provide budget inputs and make critical recommendations on program lifecycle management (scale, pivot, or sunset).

📝 Enhancement Note: The title "PX Business Designer" and the description of evaluating "commercial viability and financial scalability of patient experience concepts" strongly suggest this role falls under a broader umbrella of GTM Operations, specifically focusing on the strategic and financial aspects of patient-facing programs within a life sciences context. It requires skills often found in business operations, financial planning & analysis (FP&A), and strategy roles, with a unique application to patient experience.

📈 Primary Responsibilities

• Develop and maintain comprehensive financial models to assess the cost structures, revenue potential, and long-term economic viability of proposed patient experience (PX) initiatives.

• Apply strategic frameworks and quantitative analysis to evaluate opportunity spaces, prioritize potential PX concepts, and provide a clear business rationale for investment decisions.

• Identify and articulate key financial and non-financial value drivers (e.g., patient adherence, brand differentiation, market positioning, ecosystem value) that contribute to the overall success and impact of PX programs.

• Conduct thorough risk analysis and sensitivity scenario planning using discovery-driven planning methodologies to inform phased investment strategies and build robust business cases for new patient solutions.

• Define and inform the business architecture for patient programs, including recommendations on vendor selection, optimal funding models, and frameworks for tracking value realization and ROI.

• Partner effectively with cross-functional teams, including Finance, Data & Analytics, Commercial, Regulatory, and Experience Design, to gather inputs, align on financial projections, and provide data-driven recommendations for program scaling, adaptation, or discontinuation.

• Translate complex analytical findings and financial projections into clear, concise, and compelling executive-level presentations and reports to influence decision-making.

• Continuously monitor the performance of existing PX programs against defined KPIs and financial targets, providing insights and recommendations for optimization or strategic adjustments.

📝 Enhancement Note: The responsibilities highlight a strong analytical and strategic component, typical of roles within business operations or GTM strategy, but with a specific focus on the patient experience within the pharmaceutical industry. The emphasis on financial modeling, value drivers, and business architecture points to a need for someone who can bridge the gap between innovative patient solutions and their commercial sustainability.

🎓 Skills & Qualifications

Education:

• Bachelor’s degree in Business Administration, Finance, Economics, or a closely related quantitative field.

• An MBA or an advanced degree in a business or quantitative discipline is strongly preferred. Experience:

• 4-7 years of progressive professional experience, with a significant portion ideally within the pharmaceutical, biotechnology, life sciences, or healthcare industries.

• Demonstrated experience in roles involving financial modeling, business case development, and quantitative analysis.

• Experience in strategy development, market analysis, or operations optimization is highly beneficial. Required Skills:

• Financial Modeling & Analysis: Proven ability to build complex financial models, forecast revenue, analyze cost structures, and perform sensitivity and scenario analysis.

• Value Case Development: Expertise in quantifying financial and non-financial value drivers and articulating the ROI of strategic initiatives.

• Strategic Frameworks Application: Proficiency in applying strategic planning tools and frameworks to assess market opportunities and prioritize investments.

• Executive Communication & Presentation: Exceptional ability to translate complex data and financial concepts into clear, persuasive presentations for senior leadership.

• Cross-functional Collaboration: Demonstrated success in partnering effectively with diverse teams (Finance, Commercial, Marketing, Design, R&D) to achieve shared objectives.

• Business Architecture: Understanding of how to structure business processes, vendor relationships, and funding mechanisms for scalable programs.

• Problem-Solving: Strong analytical and critical thinking skills to identify challenges and propose data-driven solutions.

Preferred Skills:

• Human-Centered Design Principles: Experience applying or working with human-centered design methodologies to understand and improve user (patient) journeys.

• Healthcare Ecosystem Knowledge: Familiarity with healthcare access pathways, reimbursement models, payer dynamics, and regulatory considerations within the life sciences sector.

• Digital Health Technologies: Awareness of current trends and applications of digital health technologies in patient care and engagement.

• Project Management: Ability to manage multiple projects simultaneously, prioritize effectively, and meet deadlines.

📝 Enhancement Note: The required experience level (4-7 years) combined with the specific skills like financial modeling, value case development, and strategic frameworks positions this as a mid-to-senior level role within operations or strategy, demanding a candidate who can operate with a significant degree of autonomy and analytical rigor. The preference for an MBA or advanced degree suggests a strong emphasis on business acumen and strategic foresight.

📊 Process & Systems Portfolio Requirements

Portfolio Essentials:

• Financial Model Case Studies: Examples of complex financial models built to evaluate business concepts, demonstrating proficiency in forecasting, sensitivity analysis, and ROI calculation.

• Value Proposition Articulation: Demonstrations of how you've identified and quantified both financial and non-financial value drivers for strategic initiatives, linking them to enterprise KPIs.

• Strategic Opportunity Assessment: Case studies showcasing the application of strategic frameworks to identify and prioritize new business opportunities or concepts, with a clear rationale.

• Process Optimization Examples: Documentation of how you've analyzed and improved business processes, particularly those related to program implementation, financial oversight, or cross-functional workflows.

• Executive Presentation Samples: Examples of presentations delivered to senior stakeholders, effectively communicating complex financial data, strategic insights, and recommendations.

Process Documentation:

• Workflow Design & Analysis: Evidence of analyzing existing workflows related to program development, financial approval, or cross-functional collaboration, and proposing optimized alternatives.

• Implementation Strategy: Documentation outlining strategic approaches to implementing new initiatives, including considerations for vendor selection, funding allocation, and phased rollouts.

• Performance Measurement Frameworks: Examples of designing or contributing to frameworks for tracking key performance indicators (KPIs) and measuring the business impact and financial performance of programs.

📝 Enhancement Note: For a role like this, a portfolio is crucial for demonstrating practical application of financial modeling, strategic analysis, and communication skills. The emphasis should be on showcasing how the candidate has translated strategic ideas into tangible business plans and demonstrated measurable outcomes, particularly in a healthcare or life sciences context.

💵 Compensation & Benefits

Salary Range: $130,800 - $243,000 USD per year.

Explanation of Range: This range is based on the primary location of South San Francisco, California, and reflects industry benchmarks for a mid-to-senior level PX Business Designer with the specified experience and qualifications within the pharmaceutical/biotechnology sector. Factors such as specific years of experience, advanced degrees, and specialized skills will influence the final offer within this band.

Benefits:

• Discretionary Annual Bonus: Potential for an annual bonus based on individual and company performance, offering variable compensation tied to success.

• Comprehensive Health Benefits: Includes medical, dental, and vision insurance plans.

• Retirement Savings Plan: Likely includes a 401(k) plan with potential company match.

• Paid Time Off: Generous vacation, sick leave, and paid holidays.

• Life and Disability Insurance: Standard provisions for employee protection.

• Employee Assistance Program (EAP): Support services for employees and their families.

• Professional Development: Opportunities for training, conferences, and continuing education relevant to the role and industry.

• Employee Stock Purchase Plan (ESPP): Potential to purchase company stock at a discount.

Working Hours:

• Standard full-time hours are expected, typically around 40 hours per week.

• The role operates on a hybrid schedule, requiring 3 days per week on-site in South San Francisco. This offers a balance between focused work and collaborative engagement.

📝 Enhancement Note: The salary range provided is specific to California, a high cost-of-living area, and aligns with senior analytical roles in the biotech industry. The inclusion of a discretionary bonus is common for performance-driven positions. The explicit mention of "no relocation benefits" is a key detail for out-of-state candidates.

🎯 Team & Company Context

🏢 Company Culture

Industry: Biotechnology and Pharmaceuticals. Roche (Genentech) is a pioneer in the biotech industry, focused on developing innovative medicines to address unmet medical needs.

Company Size: Large enterprise (Genentech is a member of the Roche Group, a global healthcare company). This implies robust resources, established processes, and significant global reach.

Founded: Genentech was founded in 1976, making it one of the oldest and most established biotechnology companies. This history suggests a culture of innovation, scientific rigor, and a long-term commitment to patient well-being.

Team Structure:

• The role sits within the Public Affairs & Access (PAA) organization, specifically within the CMG Patient Strategy team.

• This team likely comprises specialists in patient experience design, market access, policy, and business operations.

• Collaboration is expected across various departments, including Finance, Data & Analytics (DDA), Research & Development (RDT), Activation & Capabilities Enablement, and Experience Design teams.

• The reporting structure would likely be to a manager or director overseeing Patient Strategy or a broader PAA function, with significant interaction with senior leaders. Methodology:

• Data-Driven Decision Making: Emphasizes the use of data and analytics to inform strategic choices and measure impact.

• Patient-Centricity: A core value, focusing on improving patient lives through innovative solutions and experiences.

• Cross-Functional Collaboration: Essential for integrating diverse perspectives and expertise to achieve complex goals.

• Innovation & Rigor: Balancing bold pursuit of new solutions with scientific and financial discipline.

• Business Acumen: Applying commercial and financial strategies to ensure the sustainability and scalability of initiatives.

Company Website: https://www.gene.com/

📝 Enhancement Note: Genentech's reputation for scientific innovation and patient focus, combined with its scale as part of Roche, suggests a dynamic yet structured environment. The Public Affairs & Access (PAA) and Patient Strategy teams are critical for translating scientific breakthroughs into accessible patient solutions, making this role pivotal in bridging innovation and market reality.

📈 Career & Growth Analysis

Operations Career Level: This role is positioned as a mid-to-senior level individual contributor. It requires a strong foundation in business analysis, financial modeling, and strategic thinking, with the ability to operate independently on complex projects. The "Business Designer" title implies a role that shapes and designs business solutions rather than solely executing pre-defined tasks.

Reporting Structure: The PX Business Designer will likely report to a Director or Senior Manager within the Patient Strategy or Public Affairs & Access (PAA) organization. This structure provides exposure to senior leadership and strategic decision-making processes within the commercial and access functions.

Operations Impact: The core impact of this role is to ensure that innovative patient experience initiatives are not only conceptually sound but also commercially viable and financially scalable. By providing rigorous business analysis, the PX Business Designer directly influences which patient programs receive investment, how they are structured, and ultimately, their success in reaching and supporting patients, contributing to overall business objectives and revenue generation.

Growth Opportunities:

• Specialization: Deepen expertise in patient experience strategy, healthcare economics, or commercial modeling within the life sciences sector.

• Leadership: Transition into management roles within Patient Strategy, PAA, or related commercial operations functions.

• Cross-Functional Mobility: Move into broader strategy, FP&A, or commercial operations roles within Genentech/Roche.

• Business Development: Opportunities to contribute to strategic partnerships, M&A analysis, or new venture incubation.

• Advanced Analytics: Develop expertise in leveraging advanced data analytics and digital health technologies for patient engagement and program optimization.

📝 Enhancement Note: The growth path for a PX Business Designer at a company like Genentech is strong, offering opportunities to specialize in a critical area of healthcare delivery or to move into broader strategic and operational leadership roles. The role provides a unique blend of analytical, strategic, and patient-focused work, making it attractive for those looking for impact and career development.

🌐 Work Environment

Office Type: The role is based in South San Francisco and operates on a hybrid schedule, requiring 3 days per week on campus. This suggests a modern office environment designed for collaboration, innovation, and focused work.

Office Location(s): South San Francisco, California. This location is a major hub for the biotechnology and life sciences industry, offering a vibrant ecosystem of research, development, and commercial operations.

Workspace Context:

• Collaborative Spaces: The hybrid model implies access to meeting rooms, project spaces, and common areas designed to facilitate teamwork and cross-functional interaction.

• Technology & Tools: Employees will have access to Genentech's standard IT infrastructure, including necessary software for financial modeling, data analysis, and communication. This likely includes robust internal systems and potentially access to specialized analytics platforms.

• Team Interaction: On-site days are crucial for building relationships, engaging in spontaneous discussions, and participating in team meetings and workshops. This fosters a sense of team cohesion and enables effective collaboration with colleagues in Experience Design, Finance, and other key departments.

Work Schedule:

• A standard 40-hour work week is expected.

• The hybrid arrangement provides flexibility, allowing for dedicated remote work days for focused tasks and on-site days for collaborative activities and team engagement. This balance is designed to support productivity and work-life integration.

📝 Enhancement Note: The hybrid work model is a key feature, indicating a company that balances flexibility with the recognized benefits of in-person collaboration for strategic and design-oriented roles. The South San Francisco location places the employee at the heart of the biotech industry.

📄 Application & Portfolio Review Process

Interview Process:

• Initial Screening: A recruiter or HR representative will likely conduct an initial phone screen to assess basic qualifications, interest, and cultural fit.

• Hiring Manager Interview: A conversation with the hiring manager to delve deeper into experience, responsibilities, and strategic thinking related to business design and financial analysis.

• Technical/Case Study Interview: This is a critical stage where candidates will likely be asked to present a financial model, a value case analysis, or a strategic proposal related to patient experience concepts. Preparation for this will involve showcasing portfolio work.

• Cross-Functional Team Interviews: Interviews with key collaborators from Finance, Experience Design, or Commercial teams to assess communication skills, ability to partner, and understanding of cross-functional dynamics.

• Final Interview/Panel: Potentially a final interview with senior leadership to confirm strategic alignment and overall suitability for the role and company culture.

Portfolio Review Tips:

• Curate Relevant Examples: Select 2-3 strong projects that best showcase your financial modeling, strategic analysis, and value articulation skills, ideally from the healthcare or life sciences sector.

• Structure Your Case Studies: For each project, clearly outline: the business challenge/opportunity, your role and approach, the methodologies used (e.g., financial modeling, strategic frameworks), key findings/recommendations, and the quantifiable impact or outcome.

• Highlight Metrics & ROI: Emphasize how you measured success, presented ROI, and demonstrated value (both financial and non-financial). Use clear, impactful data visualizations.

• Prepare for Q&A: Be ready to discuss your process, defend your assumptions, explain trade-offs, and articulate how your work aligns with Genentech's patient-centric mission.

• Tailor to the Role: Frame your portfolio examples in the context of evaluating and scaling patient experience initiatives, as described in the job description.

Challenge Preparation:

• Financial Modeling Exercise: Practice building financial models for new product launches or service offerings, focusing on key assumptions, sensitivity analysis, and scenario planning.

• Strategic Framework Application: Be prepared to discuss how you would use frameworks like SWOT, Porter's Five Forces, or market sizing techniques to evaluate a new patient program concept.

• Value Driver Identification: Think about how to identify and quantify non-financial value drivers specific to patient experience (e.g., improved patient satisfaction scores, reduced patient churn, enhanced brand loyalty).

• Communication Strategy: Practice articulating complex financial and strategic information concisely and persuasively, anticipating questions from various stakeholders (e.g., Finance, Marketing, R&D).

📝 Enhancement Note: The interview process is likely to be rigorous, with a strong emphasis on practical application of skills, especially through a portfolio review and potential case study. Candidates should prepare to demonstrate not just theoretical knowledge but also the ability to translate that knowledge into actionable business strategies with measurable outcomes.

🛠 Tools & Technology Stack

Primary Tools:

• Financial Modeling Software: Advanced proficiency in Microsoft Excel is essential. Experience with specialized financial planning and analysis (FP&A) software or business intelligence tools may be beneficial.

• Presentation Software: Expertise in Microsoft PowerPoint for creating compelling executive-level presentations.

• Collaboration Platforms: Proficiency with tools like Microsoft Teams, Slack, or similar for cross-functional communication and project management.

Analytics & Reporting:

• Business Intelligence (BI) Tools: Familiarity with BI platforms such as Tableau, Power BI, or QlikView for data visualization and dashboard creation to track KPIs and program performance.

• Data Analysis Tools: Experience with statistical software or data manipulation tools could be advantageous, though not explicitly listed as a requirement.

CRM & Automation:

• While not a primary focus, understanding how patient data is managed within a CRM system (e.g., Salesforce, Veeva) could provide context for patient journey mapping and program engagement.

• Familiarity with project management or workflow automation tools (e.g., Asana, Jira, Monday.com) might be useful for tracking project progress and managing cross-functional tasks.

📝 Enhancement Note: The core technical requirements revolve around advanced Excel for financial modeling and PowerPoint for communication. While specific BI or CRM tools aren't mandated, a candidate with experience in these areas will have an advantage in understanding data flow and program performance tracking within the broader organizational context.

👥 Team Culture & Values

Operations Values:

• Patient Focus: A deep commitment to improving patient lives and experiences, driving all strategic and financial decisions.

• Integrity & Ethics: Upholding the highest standards of honesty, transparency, and ethical conduct in all business dealings.

• Innovation & Boldness: Encouraging creative problem-solving and the pursuit of novel solutions to complex health challenges.

• Collaboration: Valuing teamwork and cross-functional partnerships to achieve shared goals and leverage diverse expertise.

• Excellence & Rigor: Striving for high-quality outcomes through meticulous analysis, scientific accuracy, and disciplined execution.

• Accountability: Taking ownership of projects and decisions, and being accountable for results.

Collaboration Style:

• Cross-Functional Integration: The role requires active engagement with diverse teams, fostering an environment of mutual respect and shared understanding of objectives.

• Data-Driven Dialogue: Discussions are expected to be grounded in data and analytical insights, facilitating objective decision-making.

• Constructive Feedback: A culture that encourages open and honest feedback to drive continuous improvement in processes and outcomes.

• Strategic Alignment: Emphasis on ensuring that all initiatives and decisions align with the broader company strategy and patient-centric mission.

📝 Enhancement Note: Genentech's culture is characterized by a strong scientific foundation, a patient-first ethos, and a collaborative spirit. The values emphasize both innovation and the rigor required to bring complex solutions to market, which is critical for a role that bridges creative patient experience design with commercial reality.

⚡ Challenges & Growth Opportunities

Challenges:

• Balancing Innovation with Financial Realities: A key challenge will be to evaluate novel patient experience concepts that may have uncertain financial outcomes, requiring strong justification and phased investment strategies.

• Quantifying Intangible Value: Accurately measuring and articulating the financial and non-financial value of patient experience initiatives, which can be complex and indirect.

• Cross-Functional Alignment: Navigating diverse stakeholder priorities and ensuring buy-in from various departments (e.g., Finance, Commercial, R&D, Legal) for proposed business models.

• Evolving Healthcare Landscape: Adapting to rapid changes in healthcare policy, reimbursement, and digital health technologies, and integrating these into long-term financial and strategic planning.

• Data Availability & Quality: Ensuring access to reliable data for financial modeling and KPI tracking, especially for new or innovative patient programs.

Learning & Development Opportunities:

• Deepen Healthcare Finance Expertise: Gain specialized knowledge in healthcare economics, reimbursement strategies, and value-based care models.

• Master Patient Journey Design: Develop a deeper understanding of human-centered design principles and patient empathy mapping.

• Advanced Analytics & Digital Health: Explore emerging technologies and data analytics techniques relevant to patient engagement and program optimization.

• Strategic Leadership Development: Opportunities to lead strategic initiatives, mentor junior team members, and contribute to high-level decision-making.

• Industry Conferences & Certifications: Access to relevant industry events and potential support for certifications in finance, strategy, or healthcare management.

📝 Enhancement Note: The challenges inherent in this role stem from the complexity of the healthcare industry and the need to bridge innovation with commercial viability. The growth opportunities are significant, allowing for deep specialization or broader strategic leadership within a leading biotech organization.

💡 Interview Preparation

Strategy Questions:

• "Describe a time you had to build a financial model for a new initiative with limited historical data. What assumptions did you make, and how did you validate them?" (Focus on your process, risk mitigation, and assumption justification.)

• "How would you assess the commercial viability of a patient support program that aims to improve adherence but has no direct revenue stream?" (Highlight your ability to identify and quantify non-financial value drivers and connect them to enterprise KPIs.)

• "Walk us through your process for applying strategic frameworks to evaluate new business opportunities. Which frameworks do you find most effective, and why?" (Demonstrate your analytical toolkit and strategic thinking.)

• "Imagine a patient experience concept is proposed that has significant potential patient benefit but a high upfront cost. How would you approach building a business case and recommending a phased investment strategy?" (Focus on discovery-driven planning, risk assessment, and phased rollout recommendations.) Company & Culture Questions:

• "Why are you interested in working at Genentech, and what specifically about our mission and approach to patient experience resonates with you?" (Research Genentech's recent initiatives in patient support and access.)

• "How do you approach collaborating with diverse teams, such as Finance, R&D, and Experience Design, to achieve a common goal?" (Provide specific examples of successful cross-functional projects and your role in them.)

• "Describe a situation where you had to present complex financial or strategic information to senior leadership. How did you tailor your communication to ensure understanding and influence decision-making?" (Focus on clarity, conciseness, and impact.)

• "What are your thoughts on the evolving role of digital health in patient support and access within the pharmaceutical industry?" (Show awareness of industry trends and how they might impact PX strategies.) Portfolio Presentation Strategy:

• Tell a Story: Structure your portfolio presentations around a narrative: the problem, your solution/analysis, the results, and the lessons learned.

• Focus on Impact: Quantify your achievements whenever possible. Use metrics, ROI figures, and clear statements about the business value generated.

• Explain Your 'Why': Be prepared to articulate the rationale behind your strategic choices and financial assumptions. Demonstrate critical thinking.

• Be Concise and Engaging: Respect the interviewer's time. Highlight the most critical aspects of your work and be ready to elaborate on details during Q&A.

• Connect to the Role: Explicitly draw parallels between your past work and the responsibilities of the PX Business Designer role at Genentech.

📝 Enhancement Note: The interview preparation should focus on demonstrating a blend of analytical rigor, strategic foresight, and strong communication skills, with a clear understanding of the pharmaceutical industry's unique challenges and opportunities, particularly concerning patient experience and market access.

📌 Application Steps

To apply for this operations position:

• Submit your application through the provided application link on the Roche Workday careers portal.

• Portfolio Customization: Curate your professional portfolio to highlight 2-3 key projects that best demonstrate your expertise in financial modeling, strategic analysis, and value case development, specifically tailored to healthcare or patient-focused initiatives.

• Resume Optimization: Ensure your resume clearly articulates your experience with financial modeling, business architecture, cross-functional collaboration, and quantifying value drivers. Use keywords from the job description and quantify achievements where possible.

• Interview Preparation: Practice articulating your portfolio projects, focusing on the business challenge, your methodology, the quantifiable results, and the strategic implications. Prepare to discuss how your skills align with Genentech's patient-centric mission.

• Company Research: Thoroughly research Genentech's Public Affairs & Access (PAA) organization, their patient strategy initiatives, and their overall company values. Understand their approach to innovation and patient support.

⚠️ Important Notice: This enhanced job description includes AI-generated insights and operations industry-standard assumptions. All details should be verified directly with the hiring organization before making application decisions.