Principal, Product Strategy (RWE/HEOR)

📍 Job Overview

Job Title: Principal, Product Strategy (RWE/HEOR)

Company: Komodo Health

Location: United States

Job Type: Full-Time

Category: Product Strategy / Revenue Operations

Date Posted: 2026-08-05

Experience Level: 10+ Years

Remote Status: Remote OK

🚀 Role Summary

• Owns the strategic direction and P&L for the Real-World Evidence (RWE) and Health Economics and Outcomes Research (HEOR) segment within Life Sciences customers, driving growth and market penetration.

• Leads the identification, prototyping, and successful launch of new product solutions (apps, agents, data products) that generate revenue and address critical RWE/HEOR market needs.

• Acts as the central subject matter expert for RWE/HEOR, translating market intelligence and customer needs into actionable product strategies and go-to-market plans.

• Drives innovation by leveraging AI and low-code approaches to build and iterate on product concepts, collaborating closely with Product, Engineering, Marketing, and Sales teams.

• Develops and refines the RWE/HEOR segment strategy, identifying key investment areas for product development to enhance retention and account penetration.

📝 Enhancement Note: This role is positioned as a "segment owner with a builder's mindset," indicating a strong focus on strategic ownership, market development, and product innovation within the RWE/HEOR domain. The emphasis on P&L and market entry suggests a significant revenue-generating responsibility, aligning it closely with revenue operations principles, albeit within a product strategy framework. The requirement for AI and low-code experience also points to a forward-thinking approach to product development and operational efficiency.

📈 Primary Responsibilities

• Develop and execute the RWE/HEOR segment strategy, maintaining a P&L mindset to guide investments in product development for enhanced growth, retention, and account penetration.

• Conduct regular product reviews, analyzing RWE/HEOR performance metrics, competitive landscape, and identifying portfolio gaps to inform strategic decisions.

• Maintain deep external engagement with customers, partners, and industry forums to continuously gather market intelligence, understand buyer and user needs, and monitor competitive dynamics.

• Drive the prototyping of new product concepts leveraging AI and low-code tools, developing detailed Product Requirements Documents (PRDs) and collaborating with Product Management and Engineering for iterative development and successful shipment.

• Lead market entry for new RWE/HEOR products, serving as an early internal user, defining initial value propositions, partnering with Sales on early pitches, supporting early customer implementations with forward-deployed teams, and channeling structured insights back to Product, Engineering, Marketing, and Sales.

• Provide crucial product vision and expertise during key, high-value RWE/HEOR sales engagements to drive deal closure.

• Represent Komodo Health as the primary RWE/HEOR subject matter expert at conferences, industry events, and other external forums.

📝 Enhancement Note: The responsibilities emphasize a blend of strategic planning, product development lifecycle management, market analysis, and direct customer engagement. The "shipping 3-5 solutions" outcome within the first year highlights a strong bias for action and execution. The role requires deep domain expertise combined with a strategic, P&L-oriented perspective, indicative of a senior-level position focused on business growth and product market fit.

🎓 Skills & Qualifications

Education: Bachelor's degree in a relevant field (e.g., Life Sciences, Business, Healthcare Administration, Data Science). Advanced degrees (Master's, PhD) may be preferred but are not explicitly required.

Experience: Minimum of 10+ years of deep, hands-on experience within the RWE/HEOR domain, gained through leading teams in life sciences organizations, consulting as a study lead, or managing the RWE/HEOR segment within a healthcare data/analytics company.

Required Skills:

• Expert-level understanding of the RWE/HEOR segment, including key use cases, buyer and user personas, competitive dynamics, and future market trajectory.

• Demonstrated analytical rigor, with fluency in both qualitative market intelligence and quantitative data analysis (internal signals like revenue, pipeline, product usage, win/loss; external signals like market trends, competitor moves, investor reports).

• Proven ability to build well-structured, evidence-based strategies derived from comprehensive data analysis.

• Exceptional communication and influencing skills, with the ability to articulate complex ideas into clear written, visual, and oral narratives for diverse audiences (customers, executives, cross-functional teams).

• Proven track record of operating as an integrative, cross-functional leader, effectively collaborating across Product, Sales, and Marketing functions.

• Experience using AI coding/coworking tools to build tangible outputs such as software, prototypes, workflows, or agents, demonstrating genuine curiosity and comfort with building. Preferred Skills:

• Prior product management experience, with a demonstrable track record of successfully shipping products.

• Experience with AI-driven analytics platforms and low-code development environments.

• Familiarity with Komodo Health's Healthcare Map or similar comprehensive healthcare data platforms.

📝 Enhancement Note: The emphasis on "lived the workflow, not just studied it" underscores the need for practical, hands-on RWE/HEOR experience. The requirement for AI building experience signals a shift towards more agile and technologically advanced product development methodologies within the operations and strategy functions.

📊 Process & Systems Portfolio Requirements

Portfolio Essentials:

• Demonstrated strategic planning capabilities, showcasing how market analysis was translated into actionable business plans and product roadmaps.

• Evidence of successful product launches or segment growth initiatives, detailing the strategy, execution, and measurable outcomes (e.g., revenue growth, market share increase).

• Case studies highlighting the ability to leverage data analytics and market intelligence to identify opportunities and inform strategic decisions within the RWE/HEOR space.

• Examples of cross-functional leadership, illustrating collaboration with Product, Engineering, Sales, and Marketing to achieve business objectives. Process Documentation:

• Showcase examples of how RWE/HEOR workflows were analyzed, optimized, or redesigned to improve efficiency, data quality, or analytical output.

• Illustrate experience in developing and executing go-to-market strategies for new products or solutions, including market entry plans and stakeholder enablement.

• Provide documentation or case studies on how AI or low-code tools were utilized to prototype solutions, automate processes, or enhance product capabilities within a healthcare context.

📝 Enhancement Note: Given the "builder's mindset" and emphasis on shipping products, a portfolio demonstrating tangible results and process ownership is crucial. This role requires showcasing not just strategic thinking but also the ability to execute and deliver measurable outcomes, particularly through innovative product development and market entry.

💵 Compensation & Benefits

Salary Range:

• San Francisco Bay Area and New York City: $245,000 - $288,000 USD annually.

• All Other US Locations: $213,000 - $250,000 USD annually.

Benefits:

• Comprehensive health, dental, and vision insurance plans.

• Flexible time off and paid holidays.

• 401(k) retirement plan with a company match.

• Disability insurance coverage.

• Life insurance coverage.

• Potential eligibility for performance-based bonuses and equity awards, as determined by the Company.

Working Hours: The role is listed as full-time, typically around 40 hours per week, with flexibility implied by the hybrid and remote work model.

📝 Enhancement Note: The salary ranges provided are competitive for Principal-level roles in Product Strategy, especially in high-cost-of-living areas like SF Bay Area and NYC. The detailed breakdown by location reflects standard industry practice. The inclusion of equity awards suggests a significant opportunity for long-term financial reward tied to company performance, common in growth-stage technology companies. The mention of AI integration in daily work suggests that efficiency gains through AI tools are expected and may influence productivity expectations.

🎯 Team & Company Context

🏢 Company Culture

Industry: Healthcare Data & AI Platform, focused on Real-World Evidence (RWE) and Health Economics and Outcomes Research (HEOR). Komodo Health operates at the intersection of healthcare, technology, and data analytics, aiming to reduce the global burden of disease.

Company Size: While not explicitly stated in the input, Komodo Health is a growing technology company, typically indicating a size range that allows for significant impact and cross-functional collaboration, often from 200-1000+ employees.

Founded: Komodo Health was founded with a mission to leverage data for better healthcare outcomes, established to build the "Healthcare Map" - a comprehensive view of the US healthcare system.

Team Structure:

• The Product Strategy team operates at the nexus of Product, Engineering, Sales, and Marketing.

• This role sits within the Product Strategy team, which is responsible for identifying, prototyping, launching, and scaling products across different market segments.

• The role involves close collaboration with Product Management, Engineering, Sales Enablement, Marketing, and Forward Deployed teams. Methodology:

• Data-driven decision-making, leveraging the "Healthcare Map" which integrates de-identified real-world patient data with innovative algorithms and clinical experience.

• Agile product development and iterative shipping of solutions, utilizing AI and low-code approaches.

• Customer-centric approach, with continuous engagement to understand market trends and customer needs.

• Focus on P&L ownership and driving growth within specific market segments.

Company Website: https://www.komodohealth.com/

📝 Enhancement Note: Komodo Health positions itself as a mission-driven company focused on reducing disease burden through advanced data analytics and AI. The company culture emphasizes growth, collaboration, and innovation, as reflected in their values: "be awesome, seek growth, deliver 'wow,' and enjoy the ride." The hybrid work model and distributed hubs indicate a modern approach to work arrangements.

📈 Career & Growth Analysis

Operations Career Level: This is a Principal-level role, signifying a senior individual contributor with significant strategic responsibility and domain expertise. It's a leadership position focused on driving business outcomes through product strategy within a specific market segment (RWE/HEOR).

Reporting Structure: The role reports into the Product Strategy team. While the direct manager isn't specified, it's likely a Director or VP of Product Strategy. The role requires extensive collaboration with various departments, including Product Management, Engineering, Sales, and Marketing.

Operations Impact: This role has a direct impact on revenue growth, market share, and customer retention within the RWE/HEOR segment. By defining and launching successful products, it contributes significantly to Komodo Health's overall mission and business objectives.

Growth Opportunities:

• Specialization: Deepen expertise within the RWE/HEOR domain and potentially expand into adjacent areas of healthcare data analytics or AI applications.

• Leadership: Transition into a management role within Product Strategy or Product Management, leading larger teams or broader product portfolios.

• Strategic Influence: Become a recognized thought leader in the RWE/HEOR space, representing Komodo Health at industry events and influencing the company's long-term strategic direction.

• Product Innovation: Lead the development and scaling of multiple innovative products, gaining experience in end-to-end product lifecycle management from ideation to market leadership.

📝 Enhancement Note: The Principal title suggests a high level of autonomy and influence. The "builder's mindset" and P&L ownership indicate that this role is designed for individuals who want to have a significant, measurable impact on business growth and product innovation. The career path likely involves increasing scope of responsibility and leadership opportunities within the product and strategy functions.

🌐 Work Environment

Office Type: Komodo Health operates on a hybrid work model. While they have hubs in San Francisco, New York City, and Chicago, the role is designated as "Remote OK" within the United States, suggesting that a fully remote setup is possible for this position.

Office Location(s): Hubs are located in San Francisco, New York City, and Chicago. The role can be performed from anywhere within the US.

Workspace Context:

• Collaborative Environment: The hybrid model encourages intentional in-office rhythms for hub-based employees, fostering collaboration, while also maintaining flexibility. Remote employees are expected to be adept at virtual collaboration.

• Tools & Technology: Access to Komodo Health's proprietary Healthcare Map, AI tools, and low-code platforms is implied, supporting innovative product development and data analysis.

• Team Interaction: Opportunities for interaction with diverse, ambitious professionals ("Dragons") who share a passion for the company's mission. This includes close collaboration with Product, Engineering, Sales, and Marketing teams.

Work Schedule: Standard full-time work hours (approx. 40 hours/week) are expected, with flexibility inherent in the hybrid and remote work model. The focus is on outcomes and impact rather than strict adherence to traditional office hours, especially for remote roles.

📝 Enhancement Note: The "Remote OK" status for the United States is a significant draw for operations professionals seeking location flexibility. The hybrid model indicates a balanced approach to in-person collaboration and remote autonomy, requiring strong communication and self-management skills. The company's emphasis on AI integration suggests a tech-forward and efficient work environment.

📄 Application & Portfolio Review Process

Interview Process:

• Initial Screening: A review of your resume and application to assess alignment with the required experience and skills, particularly in RWE/HEOR and product strategy.

• Hiring Manager Interview: Discussion focused on your background, experience, strategic thinking, and understanding of the RWE/HEOR market, as well as your approach to product development and P&L management.

• Cross-Functional Interviews: Interviews with key stakeholders from Product, Engineering, Sales, and Marketing teams to evaluate your ability to collaborate, influence, and integrate across departments. Expect questions on your experience with AI/low-code tools and cross-functional leadership.

• Case Study/Presentation: A potential assignment or presentation where you'll be asked to outline a product strategy for a specific RWE/HEOR challenge, demonstrate market analysis, or present a portfolio piece showcasing your strategic impact.

• Final Interview: A discussion with senior leadership to assess cultural fit, long-term vision, and overall suitability for the Principal role.

Portfolio Review Tips:

• Quantify Impact: For each project or initiative presented, clearly articulate the problem statement, your strategic approach, the actions taken, and the measurable outcomes (e.g., revenue generated, market share gained, efficiency improvements). Use specific metrics and ROI.

• Showcase Strategy & Execution: Highlight instances where you've translated market intelligence into actionable product strategies and successfully overseen product launches or segment growth.

• Demonstrate RWE/HEOR Depth: Provide examples that clearly showcase your deep understanding of RWE/HEOR use cases, workflows, and market dynamics.

• Illustrate Cross-Functional Collaboration: Include projects where you successfully partnered with Product, Engineering, Sales, and Marketing to achieve business objectives.

• Highlight AI/Building Experience: If applicable, showcase any projects where you've leveraged AI, low-code tools, or prototyping to develop solutions or improve processes.

Challenge Preparation:

• Market Analysis: Be prepared to discuss current trends, challenges, and opportunities in the RWE/HEOR market.

• Product Strategy: Practice articulating your approach to segment strategy, product ideation, development, and go-to-market execution.

• P&L Mindset: Understand how to think about revenue, costs, and profitability within a product segment.

• AI Integration: Be ready to discuss how you would leverage AI and low-code tools to enhance product offerings and operational efficiency.

• Cross-Functional Scenarios: Prepare examples of how you've navigated complex stakeholder relationships and driven consensus across different departments.

📝 Enhancement Note: The interview process is likely to be rigorous, focusing on strategic thinking, domain expertise, and execution capabilities. A strong portfolio that demonstrates tangible results, strategic foresight, and cross-functional leadership will be critical. The emphasis on AI and building suggests that candidates who can showcase practical application of these technologies will be highly competitive.

🛠 Tools & Technology Stack

Primary Tools:

• AI & Low-Code Platforms: Experience with AI coding/coworking tools and low-code development environments is explicitly required for prototyping and building solutions. Specific platforms will vary, but a general comfort and ability to learn are key.

• Product Management Tools: Familiarity with tools for PRD creation, roadmap planning, and backlog management (e.g., Jira, Confluence, Asana, Productboard).

• Data Analysis & Visualization Tools: Proficiency in analyzing data and presenting insights, potentially including tools like Tableau, Power BI, SQL, or Python libraries for data manipulation and analysis.

Analytics & Reporting:

• Business Intelligence (BI) Tools: Experience with BI platforms to track product performance, segment strategy effectiveness, and P&L metrics.

• CRM Systems: Understanding of CRM systems (e.g., Salesforce) to gain insights into sales pipeline, customer engagement, and account penetration.

• Internal Data Platforms: Familiarity with Komodo Health's proprietary Healthcare Map and associated analytical capabilities will be a significant advantage.

CRM & Automation:

• Salesforce: Likely used for sales pipeline management and customer data.

• Marketing Automation Platforms: Understanding of how marketing automation supports go-to-market strategies.

• Workflow Automation Tools: Experience with tools that can automate business processes, especially those relevant to RWE/HEOR workflows or product development.

📝 Enhancement Note: The explicit mention of AI and low-code tools for building prototypes is a distinctive requirement. This suggests a move towards more agile and rapid product development, where individuals can quickly iterate on ideas without extensive traditional engineering cycles. Proficiency in data analysis and P&L tracking tools is also paramount given the role's strategic and financial oversight responsibilities.

👥 Team Culture & Values

Operations Values:

• Be Awesome: Strive for excellence in all aspects of work, from strategic planning to product execution.

• Seek Growth: Embrace continuous learning, professional development, and opportunities to expand skills and knowledge, particularly in AI and market strategy.

• Deliver "Wow": Exceed expectations in product innovation, customer solutions, and strategic impact, creating significant value for clients and the company.

• Enjoy the Ride: Foster a positive, supportive, and collaborative work environment where challenges are met with enthusiasm and teamwork.

• Data-Driven Approach: Utilize Komodo Health's rich data assets and analytical capabilities to inform strategies, measure impact, and drive decision-making.

• Efficiency & Innovation: Champion the use of AI and modern development tools to streamline processes and create cutting-edge solutions.

Collaboration Style:

• Integrative Leadership: Act as a bridge between different departments (Product, Engineering, Sales, Marketing) to ensure alignment and drive cohesive execution.

• Cross-Functional Partnership: Proactively engage with and influence cross-functional teams, fostering a spirit of shared ownership and collective success.

• Customer-Centric Feedback Loops: Maintain open communication channels with customers and external stakeholders to gather insights that inform product development and strategy.

• Transparent Communication: Clearly articulate strategies, plans, and progress to all relevant stakeholders, ensuring alignment and buy-in.

📝 Enhancement Note: Komodo Health's values are deeply embedded in their culture, emphasizing a proactive, growth-oriented, and collaborative approach. For this role, demonstrating how you embody these values, particularly "Seek Growth" through AI adoption and "Deliver 'Wow'" through product innovation, will be key to cultural fit.

⚡ Challenges & Growth Opportunities

Challenges:

• Market Complexity: Navigating the intricate RWE/HEOR landscape, understanding diverse stakeholder needs, and staying ahead of evolving regulatory and market dynamics.

• Product-Market Fit: Ensuring new product solutions effectively address unmet needs and achieve strong adoption and revenue generation in a competitive market.

• Cross-Functional Alignment: Effectively managing priorities and driving consensus among various internal teams (Product, Engineering, Sales, Marketing) with potentially competing objectives.

• AI Integration Pace: Keeping pace with rapid advancements in AI and integrating them effectively into product strategy and development workflows.

Learning & Development Opportunities:

• Deepen RWE/HEOR Expertise: Gain unparalleled insight into the RWE/HEOR market through direct engagement with Komodo's data and customer base.

• Product Strategy Leadership: Develop advanced skills in strategic planning, P&L management, and product lifecycle leadership.

• AI & Innovation: Become an expert in leveraging AI and low-code tools for product development and business strategy.

• Industry Thought Leadership: Opportunity to represent Komodo Health at industry conferences, building personal brand and influencing market direction.

• Career Advancement: Potential to grow into senior leadership roles within Product Strategy, Product Management, or broader GTM functions at Komodo Health.

📝 Enhancement Note: This role presents a significant opportunity to shape a critical business segment using cutting-edge technology. The challenges are inherent to a fast-paced, innovative environment, and the growth opportunities are substantial for individuals eager to drive impact and develop their careers at the forefront of healthcare data and AI.

💡 Interview Preparation

Strategy Questions:

• "Describe your approach to developing a segment strategy for RWE/HEOR, considering P&L objectives and market opportunities. How would you prioritize investments?"

• "Walk us through a time you identified a significant market gap in RWE/HEOR and how you approached building a solution for it. What were the key challenges and outcomes?"

• "How do you leverage market intelligence and internal data signals to inform product strategy and roadmap decisions? Provide a specific example."

• "Imagine Komodo Health wants to enter a new adjacent market within RWE/HEOR. What would be your first steps in assessing this opportunity and developing a product strategy?" Company & Culture Questions:

• "How do you see AI playing a role in the future of RWE/HEOR product development and strategy? How would you integrate AI into your daily work at Komodo Health?"

• "Describe your experience working cross-functionally with Product, Engineering, Sales, and Marketing. How do you ensure alignment and drive execution?"

• "Our values are 'Be Awesome, Seek Growth, Deliver "Wow," and Enjoy the Ride.' How have you demonstrated these values in your previous roles?"

• "What excites you most about Komodo Health's mission to reduce the global burden of disease?" Portfolio Presentation Strategy:

• Focus on Impact: Structure your portfolio presentation around key achievements that demonstrate your strategic thinking, execution capabilities, and quantifiable results in RWE/HEOR or product strategy.

• Tell a Story: For each case study, create a narrative arc: problem, your strategy, key actions, challenges, and measurable outcomes.

• Highlight P&L & Growth: Emphasize instances where you directly influenced revenue, profitability, or market share.

• Showcase AI/Building: If you have examples of using AI or low-code tools, make them prominent.

• Be Prepared for Deep Dives: Anticipate questions about the nuances of your decisions, the data you used, and the trade-offs you made.

📝 Enhancement Note: Expect interviews to be highly strategic, focusing on your ability to think like a business owner for the RWE/HEOR segment. Be prepared to discuss your experience with AI and low-code tools, as this is a key differentiator for the role. A strong understanding of Komodo Health's mission and values will also be important for cultural fit.

📌 Application Steps

To apply for this Principal, Product Strategy (RWE/HEOR) position:

• Submit your application through the Komodo Health careers portal via the provided link.

• Tailor your resume: Highlight your 10+ years of hands-on RWE/HEOR experience, P&L ownership, product strategy development, AI/low-code building experience, and cross-functional leadership achievements. Use keywords from the job description.

• Prepare your portfolio: Curate 2-3 key projects or initiatives that best showcase your strategic impact, product launch success, market analysis skills, and ability to drive revenue growth within RWE/HEOR. Focus on quantifiable results and your strategic thought process.

• Research Komodo Health: Understand their Healthcare Map, mission, values, and recent achievements. Be ready to articulate how your skills and experience align with their goals and culture.

• Practice your narrative: Prepare to walk through your resume and portfolio highlights, clearly articulating your contributions and the impact you've made. Rehearse answers to common strategic and behavioral interview questions.

⚠️ Important Notice: This enhanced job description includes AI-generated insights and operations industry-standard assumptions. All details should be verified directly with the hiring organization before making application decisions.