Principal, Product Strategy (Commercial / Medical Affairs)

📍 Job Overview

Job Title: Principal, Product Strategy (Commercial / Medical Affairs)

Company: Komodo Health

Location: United States

Job Type: Full-Time

Category: Product Strategy / Commercial Operations / Medical Affairs Operations

Date Posted: 2026-08-05T14:54:35

Experience Level: 10+ Years

Remote Status: Remote Eligible

🚀 Role Summary

• Owns the strategic P&L for the Commercial / Medical Affairs segment, identifying key investment areas for product development to drive growth, retention, and account penetration within the Life Sciences sector.

• Leads the identification, prototyping, shipping, and scaling of new products, applications, data products, and skill suites tailored to Commercial / Medical Affairs workflows and market needs.

• Acts as the primary subject matter expert and internal/external evangelist for Komodo's product portfolio within the Commercial / Medical Affairs market, representing the company at industry forums and conferences.

• Integrates AI and low-code approaches into product concept prototyping and development, collaborating closely with Product Management, Engineering, Sales, and Marketing teams to bring solutions to market.

• Drives market entry for new Commercial / Medical Affairs products, serving as an early internal user, defining value propositions, supporting early pitches, assisting with customer implementations, and gathering structured feedback for continuous product improvement.

📝 Enhancement Note: This role is a strategic segment owner with a strong emphasis on building and scaling products within the Commercial/Medical Affairs domain. The "Principal" title suggests a senior individual contributor role with significant autonomy and P&L accountability, requiring deep domain expertise and a builder's mindset. The emphasis on AI and low-code tools indicates a forward-thinking approach to product development and operational efficiency.

📈 Primary Responsibilities

• Develop and refine the Commercial / Medical Affairs segment strategy, including defining target market segments, customer needs, and competitive positioning with a P&L mindset.

• Conduct regular product reviews for the Commercial / Medical Affairs portfolio, analyzing performance metrics, competitive dynamics, and identifying portfolio gaps or opportunities for enhancement.

• Engage proactively with external stakeholders, including customers, partners, and industry thought leaders, to gather market intelligence, understand evolving buyer and user needs, and stay abreast of competitive landscapes.

• Lead the ideation and prototyping of new product concepts leveraging AI and low-code tools, translating these into detailed Product Requirements Documents (PRDs) and collaborating with Product and Engineering for iterative development and launch.

• Manage the market entry and early adoption phase for new Commercial / Medical Affairs products, acting as an early internal user, articulating the value proposition, assisting Sales with pitches, supporting customer implementations, and channeling feedback to relevant teams.

• Provide Product vision and strategic expertise for high-value Real-World Evidence (RWE) and Health Economics and Outcomes Research (HEOR) deals.

• Represent Komodo Health as the Commercial / Medical Affairs subject matter expert at key industry conferences, events, and client engagements.

• Collaborate closely with Sales, Marketing, and Product teams to develop effective go-to-market strategies, sales enablement materials, and product marketing plans for the Commercial / Medical Affairs segment.

• Drive continuous improvement and optimization of existing products within the Commercial / Medical Affairs portfolio based on performance data, customer feedback, and market trends.

📝 Enhancement Note: The responsibilities clearly outline a product leadership role focused on a specific market segment. The emphasis on "shipping solutions," "market entry," and "P&L mindset" indicates a strong bias towards execution and revenue generation. The requirement to "own segment strategy" and "bring Product vision" underscores the strategic nature and influence of this position.

🎓 Skills & Qualifications

Education: While not explicitly stated, a Bachelor's degree in a relevant field (e.g., Business, Life Sciences, Healthcare Administration, Marketing) is typically expected for roles requiring 10+ years of experience. Advanced degrees (MBA, MPH, PhD) may be preferred.

Experience: 10+ years of deep, hands-on experience within the Commercial / Medical Affairs functions of life sciences organizations, or equivalent experience in consulting or leading a segment within a healthcare data/analytics company.

Required Skills:

• Expert-level understanding of the Commercial / Medical Affairs segment, including key use cases, buyer and user personas, competitive dynamics, and future market trends.

• Demonstrated ability to own and refine segment strategy with a P&L mindset, focusing on growth, retention, and account penetration.

• Proven track record in identifying, prototyping, and shipping new product solutions (apps, agents, data products) that solve real customer problems.

• Strong analytical rigor, with fluency in both qualitative market intelligence and quantitative data analysis (internal signals like revenue, pipeline, product usage; external signals like market trends, competitor moves).

• Exceptional communication, presentation, and influencing skills, capable of translating complex ideas into clear narratives for diverse audiences.

• Experience operating as an integrative, cross-functional leader, collaborating effectively across Product, Engineering, Sales, Marketing, and other functions.

• Hands-on experience using AI coding/coworking tools for building software, prototypes, workflows, or agents, demonstrating genuine curiosity and comfort with building.

• Deep understanding of healthcare data and analytics, particularly real-world data (RWD) and its application in Commercial and Medical Affairs. Preferred Skills:

• Prior product management experience with a demonstrated track record of successfully shipping products.

• Experience with Health Economics and Outcomes Research (HEOR) and Real-World Evidence (RWE) methodologies and applications.

• Familiarity with low-code development platforms and rapid prototyping techniques.

• Experience representing a company at industry forums, conferences, and events.

• Familiarity with AI-driven insights generation and predictive modeling in a commercial or medical affairs context.

📝 Enhancement Note: The "10+ years of deep, hands-on experience" is a critical filter. The emphasis on "lived the workflow, not just studied it from the outside" strongly suggests candidates with direct experience within pharmaceutical or biotech companies' commercial or medical affairs departments will be highly prioritized. The AI/low-code requirement is a modern differentiator.

📊 Process & Systems Portfolio Requirements

Portfolio Essentials:

• Demonstrations of strategic planning and market analysis, showcasing how you've identified market opportunities within Commercial / Medical Affairs.

• Case studies of new products or solutions you've conceived, prototyped, and successfully brought to market, highlighting the iterative development process.

• Examples of how you've used data (qualitative and quantitative) to inform strategy, product decisions, and measure performance.

• Evidence of cross-functional leadership and successful collaboration with Product, Engineering, Sales, and Marketing teams.

• Prototypes or examples of solutions built using AI or low-code tools, demonstrating your "builder's mindset." Process Documentation:

• Documented examples of market assessment frameworks and competitive analysis methodologies used to inform strategy.

• Examples of Product Requirements Documents (PRDs) or similar artifacts used to define product scope and features.

• Case studies detailing the process of market entry and early customer implementation for new products.

• Process flows illustrating how you've integrated customer feedback into product iteration cycles.

📝 Enhancement Note: Given the role's focus on product strategy and execution, a portfolio showcasing strategic thinking, product development lifecycle management, and cross-functional collaboration will be essential. Demonstrating the ability to build and iterate using modern tools like AI and low-code will be a significant advantage.

💵 Compensation & Benefits

Salary Range:

• San Francisco Bay Area and New York City: $245,000 - $288,000 USD per year

• All Other US Locations: $213,000 - $250,000 USD per year

Benefits:

• Comprehensive health, dental, and vision insurance.

• Flexible time off and holidays.

• 401(k) with company match.

• Disability insurance.

• Life insurance.

• Equity awards.

• Leaves of absence in accordance with applicable state and local laws and regulations and company policy.

Working Hours: Expected 40 hours per week, with flexibility inherent in a remote-eligible, senior role.

📝 Enhancement Note: The salary ranges are competitive for a Principal-level role in the specified locations, reflecting the seniority and strategic impact expected. The inclusion of equity awards suggests potential for significant upside. The pay transparency note indicates that compensation is determined by factors including skills, experience, location, and market demand.

🎯 Team & Company Context

🏢 Company Culture

Industry: Healthcare Technology / Data & AI

Company Size: The job listing does not specify the exact company size, but Komodo Health is a well-established player in the healthcare analytics space, suggesting a mid-to-large size organization with significant growth. (Based on external data, Komodo Health has 500-1000 employees).

Founded: The founding date is not provided, but Komodo Health was founded in 2010, indicating a mature company with established processes and a history of innovation.

Team Structure:

• The Product Strategy team operates at the intersection of Product, Engineering, Sales, and Marketing.

• This role sits within the Product Strategy team and is a segment owner, implying close collaboration with Product Management, Engineering leads, Sales leadership, and Marketing functions.

• The role requires acting as a bridge between market needs and internal product development capabilities. Methodology:

• Data-Driven Strategy: Employs a combination of qualitative market intelligence and quantitative data analysis to inform strategic decisions and product development.

• Agile Product Development: Utilizes iterative approaches, prototyping with AI and low-code, and cross-functional collaboration to ship and scale products.

• Customer-Centric Innovation: Focuses on understanding and solving real problems for Commercial / Medical Affairs customers through targeted product solutions.

• AI Integration: Encourages and expects the integration of AI into daily workflows for efficiency and insight generation, positioning AI as foundational.

Company Website: https://www.komodohealth.com/

📝 Enhancement Note: Komodo Health positions itself as a leader in healthcare data and AI. The company culture emphasizes innovation, growth, and a mission-driven approach ("Reduce the Burden of Disease"). The "Dragon" employee identity and values like "be awesome, seek growth, deliver 'wow,' and enjoy the ride" suggest a dynamic and collaborative work environment.

📈 Career & Growth Analysis

Operations Career Level: Principal, Product Strategy. This is a senior individual contributor role, often considered a leadership position for subject matter experts who drive significant strategic initiatives and product outcomes without direct people management responsibility. It implies a high degree of autonomy and influence.

Reporting Structure: While not explicitly stated, a Principal Product Strategist typically reports to a Director or VP of Product Strategy or Product Management. They are expected to work closely with cross-functional leaders in Engineering, Sales, and Marketing.

Operations Impact: This role has a direct impact on revenue growth and market penetration within a critical segment (Commercial / Medical Affairs) for Komodo Health. By identifying and shipping successful products, the individual will drive customer acquisition, retention, and expansion, directly contributing to the company's overall business objectives and mission.

Growth Opportunities:

• Deep Domain Expertise: Opportunity to become the foremost expert in the Commercial / Medical Affairs segment for Komodo Health and the broader industry.

• Product Leadership: Potential to transition into broader Product Management leadership roles or expand the scope of segment ownership.

• Strategic Influence: Significant opportunity to shape the strategic direction and product roadmap of a key business unit.

• AI & Innovation: Exposure to cutting-edge AI and low-code technologies, fostering continuous learning and skill development in emerging tech.

• Industry Recognition: Opportunity to represent Komodo Health at industry forums, enhancing personal brand and industry standing.

📝 Enhancement Note: This role is positioned for individuals who want to drive significant product and business impact through strategic expertise and execution, rather than traditional people management. The "Principal" title suggests a path for highly skilled individual contributors.

🌐 Work Environment

Office Type: Hybrid work model with hubs in San Francisco, New York City, and Chicago. Some roles can be performed from anywhere in the country, others are region-specific, and some are hub-based. Expectations for in-office presence will be clear before joining.

Office Location(s): San Francisco, New York City, Chicago (as hubs). Remote work is an option within the United States.

Workspace Context:

• Collaborative Hubs: For those working near hubs, there will be intentional in-office rhythms to foster collaboration.

• Remote Flexibility: For remote employees, the environment supports autonomy and requires strong self-management and communication skills.

• Technology-Enabled: As a data and AI company, expect access to robust technology infrastructure and tools necessary for data analysis, product development, and collaboration.

Work Schedule: The role is expected to be 40 hours per week. While the company offers flexibility, the strategic nature of the role and the need to collaborate across functions may require adaptability in working hours, especially when engaging with customers or during critical product launch phases.

📝 Enhancement Note: The hybrid model indicates a balance between in-office collaboration and remote flexibility. The company emphasizes clarity on expectations regarding work location and in-office presence. For remote candidates, strong communication and self-discipline are key.

📄 Application & Portfolio Review Process

Interview Process:

• Initial Screening: Review of resume and portfolio to assess experience alignment with Commercial / Medical Affairs, product strategy, and AI/building capabilities.

• Hiring Manager Interview: Discussion focused on domain expertise, strategic thinking, P&L mindset, and understanding of Komodo Health's market.

• Cross-Functional Interviews: Meetings with peers and leaders from Product, Engineering, Sales, and Marketing to assess collaboration style, communication skills, and ability to influence.

• Case Study/Presentation: Candidates may be asked to present a strategic proposal, product concept, or analysis related to the Commercial / Medical Affairs segment, demonstrating their approach to problem-solving and strategic planning.

• Executive Interview: Final interview with senior leadership to assess overall fit, strategic vision, and alignment with company values.

Portfolio Review Tips:

• Quantify Impact: Showcase how your strategies and product initiatives have driven measurable business outcomes (e.g., revenue growth, market share increase, cost savings, efficiency improvements).

• Highlight Strategic Thinking: Clearly articulate the market problem, your proposed solution, the strategic rationale, and how it aligns with business objectives.

• Demonstrate "Builder's Mindset": Include examples of products, prototypes, or workflows you've personally built or significantly contributed to, especially those using AI or low-code tools.

• Showcase Cross-Functional Collaboration: Provide examples of how you've successfully partnered with different departments to achieve product launch and market success.

• Tailor to Komodo: Research Komodo Health's Healthcare Map and their mission to reduce the burden of disease. Frame your experience and portfolio examples in the context of their business and values.

Challenge Preparation:

• Be prepared to discuss your approach to segment strategy, market analysis, and product roadmap development.

• Practice articulating complex ideas concisely and persuasively for various audiences.

• Study Komodo Health's product offerings, particularly how they serve the Commercial / Medical Affairs segment.

• Think about how AI and real-world data can be leveraged to solve unmet needs in Commercial and Medical Affairs.

• Prepare specific examples from your experience that demonstrate your ability to build, influence, and drive results.

📝 Enhancement Note: The interview process will likely assess both deep domain expertise and strategic/execution capabilities. A strong portfolio that bridges strategy with tangible product development and cross-functional execution is critical. The emphasis on "building" with AI and low-code suggests candidates should be ready to discuss practical application.

🛠 Tools & Technology Stack

Primary Tools:

• AI & Low-Code Platforms: Experience with AI coding/coworking tools and low-code development environments is explicitly required for prototyping and building. Specific platforms are not mentioned, indicating a need for general proficiency and curiosity.

• Product Management Tools: Familiarity with tools for PRD creation, roadmap planning, and collaboration (e.g., Jira, Confluence, Aha!, Productboard).

• Data Analysis & Visualization: Proficiency in tools for analyzing market data, internal signals, and product performance. This could include SQL, Python/R for data manipulation, and visualization tools like Tableau, Power BI, or Looker.

• CRM & Sales Enablement Platforms: Understanding of how product strategy integrates with CRM (e.g., Salesforce) and sales enablement tools to drive adoption and revenue.

Analytics & Reporting:

• Tools for analyzing customer usage data, revenue metrics, pipeline data, and competitive intelligence.

• Experience with business intelligence (BI) platforms for reporting and dashboard creation to track segment performance. CRM & Automation:

• Understanding of how products integrate into broader commercial and medical affairs workflows, which often rely on CRM systems and automation tools.

• Familiarity with data integration concepts relevant to healthcare data platforms.

📝 Enhancement Note: The explicit requirement for AI and low-code tools is a key differentiator. Candidates should be prepared to discuss their experience and comfort level with these technologies. Proficiency in standard Product Management and Data Analysis tools is also expected.

👥 Team Culture & Values

Operations Values:

• Be Awesome: Strive for excellence in all aspects of work, from strategy development to product execution.

• Seek Growth: Embrace learning, continuous improvement, and professional development, both personally and for the segment.

• Deliver "Wow": Exceed expectations in delivering innovative solutions and exceptional value to customers and stakeholders.

• Enjoy the Ride: Maintain a positive, supportive, and collaborative attitude while working towards ambitious goals.

• AI as Foundational: Actively integrate AI into daily work to drive efficiency, uncover insights, and contribute to Komodo's AI leadership.

Collaboration Style:

• Cross-functional Integration: Works seamlessly across Product, Engineering, Sales, and Marketing to translate market needs into actionable product strategies and successful launches.

• Data-Informed Decision Making: Relies on both qualitative and quantitative data to guide strategies and product decisions.

• Proactive Communication: Maintains clear and consistent communication with internal and external stakeholders to ensure alignment and drive progress.

• Mission-Oriented: Driven by Komodo Health's mission to reduce the global burden of disease, fostering a sense of shared purpose.

📝 Enhancement Note: The company values are deeply embedded in the culture and expected to be reflected in the daily work and interactions of employees. The emphasis on AI integration highlights a forward-looking and technologically adept approach.

⚡ Challenges & Growth Opportunities

Challenges:

• Market Complexity: Navigating the intricate and rapidly evolving landscape of Commercial and Medical Affairs within the Life Sciences sector.

• Product-Market Fit: Ensuring new products and solutions accurately address unmet needs and achieve strong adoption within target customer segments.

• Cross-Functional Alignment: Maintaining alignment and driving execution across multiple departments (Product, Engineering, Sales, Marketing) with potentially competing priorities.

• AI Integration at Scale: Effectively leveraging AI and low-code tools to deliver tangible business value and competitive advantage for Komodo Health and its clients.

• Data Interpretation: Synthesizing diverse data sources (market intelligence, product usage, customer feedback) into actionable strategies.

Learning & Development Opportunities:

• Deepening Domain Expertise: Becoming a recognized leader in Commercial / Medical Affairs product strategy within the healthcare data and AI space.

• Advanced Product Development: Gaining hands-on experience with cutting-edge AI and low-code technologies for product innovation.

• Strategic Business Acumen: Developing a strong P&L ownership and segment strategy development skillset.

• Industry Exposure: Opportunities to present at industry conferences and engage with key opinion leaders.

• Mentorship: Potential to learn from and collaborate with experienced leaders across Komodo Health.

📝 Enhancement Note: The role presents significant opportunities for growth by tackling complex challenges in a dynamic industry, leveraging advanced technologies, and directly influencing business strategy and product innovation.

💡 Interview Preparation

Strategy Questions:

• "Describe your approach to developing a segment strategy with P&L accountability for a specific market like Commercial / Medical Affairs. What key inputs would you prioritize?"

• "Walk us through a time you identified a significant market gap or unmet need and how you went about prototyping and validating a solution. What was the outcome?"

• "How do you balance quantitative data analysis with qualitative market intelligence when making strategic recommendations?"

• "Describe a situation where you had to influence cross-functional teams (e.g., Product, Engineering, Sales) to adopt your strategic vision or product roadmap. What was your approach and the result?" Company & Culture Questions:

• "What excites you about Komodo Health's mission to reduce the burden of disease and our position in the healthcare data and AI market?"

• "How do you see AI playing a role in the future of Commercial and Medical Affairs, and how would you integrate that into product strategy?"

• "Based on our values (Be Awesome, Seek Growth, Deliver 'Wow,' Enjoy the Ride), how would you contribute to our team culture?"

• "How do you approach collaboration with Sales and Marketing teams to ensure successful product launches and market adoption?" Portfolio Presentation Strategy:

• Structure Your Story: For each key portfolio item, clearly articulate the problem, your role, the solution developed, the process followed (emphasizing strategy, data, and cross-functional work), and the quantifiable results.

• Highlight "Builder" Aspect: For any AI or low-code projects, be ready to explain your specific contributions to the building process.

• Focus on Impact: Emphasize the business impact of your work – revenue generated, market share gained, customer acquisition/retention, efficiency improvements.

• Demonstrate Strategic Thinking: Clearly connect your work to broader market trends and business objectives.

• Be Concise and Engaging: Practice presenting your portfolio concisely, allowing time for Q&A and deeper dives into specific projects.

📝 Enhancement Note: Interviewers will be looking for a blend of strategic vision, deep domain expertise, a hands-on "builder's mindset" with AI/low-code, and strong cross-functional leadership. Be prepared to provide specific, quantifiable examples that demonstrate your impact.

📌 Application Steps

To apply for this operations position:

• Submit your application through the Komodo Health careers portal via the provided link.

• Portfolio Preparation: Curate a portfolio that highlights your experience in Commercial / Medical Affairs strategy, product development, and any AI/low-code building initiatives. Focus on case studies demonstrating strategic thinking, cross-functional collaboration, and measurable business impact.

• Resume Optimization: Tailor your resume to emphasize 10+ years of hands-on experience in the specified domains, highlight your P&L mindset, strategic planning abilities, and experience with AI/low-code tools. Use keywords from the job description.

• Interview Practice: Prepare to discuss specific examples of your strategic contributions, product development lifecycle management, and cross-functional leadership. Practice articulating your approach to market analysis and product strategy.

• Company Research: Thoroughly research Komodo Health, their Healthcare Map, their mission, and their values. Understand their current product offerings and how they serve the Commercial / Medical Affairs segment.

⚠️ Important Notice: This enhanced job description includes AI-generated insights and operations industry-standard assumptions. All details should be verified directly with the hiring organization before making application decisions.

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